Evaluation of Vitamin D’s Effect in Reduction of Obesity in a Rabbit Model
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الملخص
Background: Obesity is currently a global health problem, and it is one of the risk factors leading to a high number of deaths per year. Several studies were carried out to identify the causes of overweight and obesity. Vit. D deficiency is presumed to have an effect on the development of obesity.
Objective: This study's objective is to evaluate the impact of vitamin D in reduction of obesity in a rabbit model and its effect on the lipid profile.
Methods: Ten male rabbits were split up into two groups for the experiment; (a) control group (with a fatty rich diet), (b) vitamin D group (with a fatty rich diet + vitamin D supplementation for 4 weeks). Blood samples for lipid profile (TG, LDL, and HDL) were collected before and at the end of the study, and their body weights were measured as well.
Results: Following four weeks of the trial, the animals in the control group weighed significantly more than those in the vitamin D group. The increase in serum TG and LDL were significant for the control animals in related to the vitamin D animals. In addition, there is a significant rise in the good serum HDL in the control group compared to the vitamin D group.
Conclusion: The results of this study demonstrated that vitamin D has an important effect in reduction of body weight and obesity.
التنزيلات
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هذا العمل مرخص بموجب Creative Commons Attribution 4.0 International License.
تلتزم المجلة اليمنية للعلوم الطبية رخصة مؤسسة المشاع الإبداعي من فئة (CC BY)، والتي تتيح إعادة استخدام البحث بأي شكل من الأشكال شريطة الاستشهاد بالمؤلف (المؤلفين) والمجلة. وتعتبر المجلة أن المؤلف (المؤلفون) موافق على هذه السياسة بمجرد تقديم البحث للنشر.