Hematological parameters among pregnant and non-pregnant women in Aldalea Governorate, Yemen: A Comparative Study
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Abstract
Background: Complete blood count (CBC) is an essential diagnostic tool for assessing overall health and monitoring physiological changes. Pregnancy induces specific hematological modifications reflecting both physiological adaptations and potential pathological conditions.
Objective: This study aimed to assess hematological parameters among pregnant and non-pregnant women in Aldalea Governorate, Yemen, and to identify significant differences that may affect clinical interpretations.
Methods: A comparative cross-sectional study was conducted on 164 women (128 pregnant and 36 non-pregnant) between May and December 2023. CBC analysis was performed using the Sysmex XP-300 hematological analyzer. Data were analyzed using independent t-tests via SPSS version 21, with statistical significance set at p<0.05. Results: Pregnant women exhibited a significantly lower packed cell volume (PCV) compared to non-pregnant women (32.4 ± 4.73% vs. 37 ± 2.41%, p<0.001). Additionally, differential white blood cell analysis revealed a significantly elevated neutrophil percentage (60.3 ± 9.3% vs. 44.3 ± 11.83%, p=0.04) and a significantly reduced lymphocyte percentage (33.8 ± 8.85% vs. 45.1 ± 9.35%, p=0.011) among pregnant women. In contrast, differences in hemoglobin levels, red blood cell count, mean corpuscular volume, and platelet counts were not statistically significant.
Conclusion: The study demonstrates that pregnancy in Aldalea is associated with a significant reduction in PCV and marked alterations in white blood cell differentials, indicative of hemodilution and immunological adaptations. These findings underscore the need for establishing region-specific hematological reference intervals for pregnant women to enhance diagnostic accuracy and optimize clinical management.
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Hematological parameters , pregnant women ,Aldalea,Yemen.
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