A Comparative Quality Study of Selected Locally Manufactured and Imported Medicines in Yemeni Market

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Published Dec 1, 2010
DOI https://doi.org/10.20428/yjms.v4i1.250

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Khaled Al-Tahami
Assistant Professor of Pharmaceutics, Department of Pharmacy, Faculty of Medical Sciences, University of Science and Technology

Abstract

Objective: In a poor country like Yemen, the cost is a crucial factor in determining the accessibility of patient to health care services. In such situations, locally manufactured medicines seem like an attractive choice due to their cheaper prices. In our work, the quality control of selected pharmaceutical products (original and locally manufactured medicines containing esomperazole and hyoscine butylbromide) was investigated. Methods: Standard USP quality control tests (disintegration, friability, dissolution, and content assay) were run on all the tested products. Results: When we compared between the quality of selected locally manufactured medicines, another generic alternative available in the Yemeni market, and the original parent drug, we observed that the Yemeni products have equal quality compared to original products and superior quality to the other imported generic product. Conclusion: A rational substitution for the expensive original pharmaceutical products can be carried out using high quality locally manufactured generic products.

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Keywords

Quality control studies, comparative evaluation, locally manufactured medicines, esomeperazole, and hyoscine butylbromide

Issue
Vol. 4 No. 1 (2010)
Section
Original Article
Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

YJMS publishes Open Access articles under the Creative Commons Attribution (CC BY) license. If author(s) submit their manuscript for consideration by YJMS, they agree to have the CC BY license applied to their work, which means that it may be reused in any form provided that the author(s) and the journal are properly cited. Under this license, author(s) also preserve the right of reusing the content of their manuscript provided that they cite the YJMS.

How to Cite
Al-Tahami, K. (2010). A Comparative Quality Study of Selected Locally Manufactured and Imported Medicines in Yemeni Market. Yemeni Journal for Medical Sciences, 4(1), 8–13. https://doi.org/10.20428/yjms.v4i1.250