An Investigation of the Phytochemical Composition and Antimicrobial Activities of Commiphora Africana Stem Bark Extract

Abstract

Commiphora africana, a traditional African medicinal plant, has been used to cure numerous illnesses. This study studied the phytochemical content and antibacterial properties of its stem bark extract. Phytochemical analysis identified the presence of alkaloids, flavonoids, glycosides, and terpenoids. The extract demonstrated significant antibacterial effects against a variety of pathogenic microorganisms. Staphylococcus aureus, Escherichia coli, and Salmonella typhi were tested, and the minimum inhibitory concentration (MIC) was determined. The values for these pathogens ranged between 0.5 and 2.5 mg/mL, highlighting its potent antimicrobial potential. The antioxidant activity of the extract was also examined, demonstrating a strong scavenging capacity. The findings imply that the stem bark extract of Commiphora africana is a possible source of natural antibacterial and antioxidant compounds, supporting its traditional usage in medicine. Further investigations are needed to extract and define the bioactive molecules responsible for these activities.